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The Keystone Program in Blood Cell Development and Cancer
The Progress 2008 - 2009
Publications
Lauritsen JPH, Wong GW, Lee SY, Lefebvre JM, Ciofani M, Rhodes M, Kappes DJ, Zúñiga-Pflücker JC, and Wiest DL. Marked induction of the helix-loop-helix protein Id3 promotes the gamma-delta T cell fate and renders their functional maturation Notch-independent. Immunity. 2009 Oct 16;31(4):565-75. PubMed
Borghaei H, Smith MR, Campbell KS. Immunotherapy of Cancer. Eur J Pharmacol. 2009 Dec 25;625(1-3):41-54. Epub 2009 Oct 20. PubMed
Gitelson E, Al-Saleem T, Smith MR. Lymphomatoid granulomatosis: challenges in diagnosis and treatment. Clin Adv Hematol Oncol. 2009 Jan;7(1):68-70. PubMed
Timakhov RA, Tan Y, Rao M, Liu Z, Altomare DA, Pei J, Xu J, Wiest DL, Favorova OO, Knepper JE, Testa JR. Recurrent chromosomal rearrangements implicate oncogenes that contribute to T-cell lymphomagenesis in Akt2 transgenic mice. Genes Chromosomes Cancer, 2009. In Press.
MacFarlane AW 4th, Yamazaki T, Fang M, Sigal LJ, Kurosaki T, Campbell KS. Enhanced NK-cell development and function in BCAP-deficient mice. Blood. 2008 Jul 1;112(1):131-40. (Featured) PubMed
Shafer D, Wu H, Al-Saleem T, Reddy K, Borghaei H, Lessin S, Smith M. 2008. Cutaneous precursor B-cell lymphoblastic lymphoma in 2 adult patients: clinicopathologic and molecular cytogenetic studies with a review of the literature. Arch Dermatol. 144:1155-62. PubMed
Tan Y, Timakhov RA, Rao M, Altomare DA, Xu J, Liu Z, Gao Q, Jhanwar SC, Di Cristofano A, Wiest DL, Knepper JE, Testa JR. A novel recurrent chromosomal inversion implicates the homeobox bigene pair Dlx5/Dlx6 in T-Cell lymphomas from Lck-Akt2 transgenic mice. Cancer Research. 2008 Mar 1;68(5):1296-302. PubMed
Anderson SJ, Lauritsen JP, Hartman MG, Foushee AM, Lefebvre JM, Shinton SA, Gerhardt B, Hardy RR, Oravecz T, Wiest DL. Ablation of ribosomal protein L22 selectively impairs alphabeta T cell development by activation of a p53-dependent checkpoint. Immunity. 2007 Jun;26(6):759-72. Epub 2007 Jun 7. PubMed